منابع مشابه
Prognostic biomarkers in osteoarthritis.
PURPOSE OF REVIEW Identification of patients at risk for incident disease or disease progression in osteoarthritis remains challenging, as radiography is an insensitive reflection of molecular changes that presage cartilage and bone abnormalities. Thus there is a widely appreciated need for biochemical and imaging biomarkers. We describe recent developments with such biomarkers to identify oste...
متن کاملBiomarkers in osteoarthritis.
PURPOSE OF REVIEW Osteoarthritis is a chronic disease characterized by progressive destruction of articular cartilage and subchondral bone, and synovial reaction. Clinical and radiologic findings that form the basis of the diagnosis of osteoarthritis are poorly sensitive for monitoring the progression of the disease. Biologic markers reflecting quantitative and dynamic changes of joint tissue t...
متن کاملBiomarkers in osteoarthritis
Biomarkers aid the study of osteoarthritis (OA) in a number of different ways. In this article we summarise briefly their multiple uses and reflect on how the study reported in a previous edition of Arthritis Research & Therapy should promote further investigation of cartilage oligomeric matrix protein (COMP). COMP is foremost among hitherto investigated biomarkers and is most consistently show...
متن کامل7. Biomarkers in osteoarthritis
The risk of osteoarthritis (OA), the disease stage, and its progression are generally assessed by basic pain measurements, clinical examination, and conventional X-rays. These techniques lack sensitivity in disease monitoring, especially in the early stages of disease, and need to be further developed using additional variables to optimize clinical studies and disease management. In recent year...
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ژورنال
عنوان ژورنال: Current Opinion in Rheumatology
سال: 2013
ISSN: 1040-8711
DOI: 10.1097/bor.0b013e32835a9381